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X

Xanthoma

Etiology: disorders of lipid metabolism (dyslipidemia) or occur in histiocytosis

Appearance: soft, yellow or skin colored papules or plaques

Location/Types:

  • medial canthus of upper eyelid = xanthelasma

  • over pressure areas (knees, elbows, heels) = tuberous xanthoma

  • extensor surfaces (buttock, shoulders) = eruptive xanthoma

Xeroderma Pigmentosum (XP)

Etiology: mutation in nucleotide excision repair (NER)

Inheritance: AR

Appearance: born with normal skin, but with increased sun exposure, patients develop hyperpigmented and hypo pigmented macules

Location: sun exposed skin

Prog: premature aging; die earlier from skin cancers

Xerosis Cutis/Dry Skin

Etiology: skin is lacking moisture in stratum corneum

Appearance: rough, scaly plaque

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