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K

Kaposi Sarcoma

Etiology: HHV-8

Types:

  • Classic: often affects middle aged men of Mediterranean or Eastern European descent

  • Endemic: occurs in sub-Saharan Africans

  • Iatrogenic: due to immunosuppressive drugs (esp. kidney transplants)

  • AIDS-associated: most common

Appearance: red, purple, or brown patches or nodules

Location: lower extremities (esp. classic type), when disseminates it spreads to mouth, lungs, liver, other organs

Kawasaki Disease

Etiology: 
 

Medium-vessel vasculitis

 

Description: polymorphous / morbilliform (measles like) / targetoid skin lesions -> desquamating rash (peeling of extremities)

 

Location: trunk and extremities 

Keloid

Etiology: 
 

Cause: dysregulation of the normal healing process resulting in excessive production of collagen, elastin, proteoglycans, and extracellular matrix proteins

 

Description: Purplish-red, firm, smooth, and raised; can occur years after injury and grows beyond the initiating wound area

Keratoacanthoma (KA)

Etiology: form of SCC (UV exposure)

Appearance: flesh-colored or pink dome-shaped nodule with central keratin plug

Location: face, neck, dorsal of upper extremities

Tx: excision

Keratoderma Blennorrhagica

Etiology: 
 

Associated with: reactive arthritis (Chlamydia)

 

Description: painless desquamative psoriatic-like papulosquamous eruption 

 

Location: commonly found on the palms + soles but may spread to the scrotum, scalp, + trunk

Keratoelastoidosis Marginalis

Etiology: 
 

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Keratosis Pilaris (KP)

Etiology: 
 

Cause: abnormal keratinization of the upper portion lining of the hair follicle

 

Description: ‘goosebump’ or ‘chicken skin’ appearance

 

Location: most common on posterior arms

Keratosis spinulosa

Etiology: 

Kindler Syndrome

Etiology: AR mutation of KIND-I

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