R
Raynaud’s Phenomenon
Etiology:
Description: vasospastic event where digits change from blue to white to red
Associated with: Scleroderma (CREST), SLE, Cold AIHA
Refsum disease
Etiology:
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Define: rare, inherited metabolic disorder where the body cannot properly break down a type of fat called phytanic acid = leads to a buildup of phytanic acid in the blood and tissues, causing a range of symptoms including vision loss, hearing loss, nerve damage, and skin abnormalities
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Diagnosed via blood tests showing elevated phytanic acid levels
Reticulohistiocytoma (Solitary Epithelioid Histiocytoma)
Etiology:
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Appearance: solitary red to brown to yellow papule or nodule in adults
Richner Hanhart Syndrome
Etiology:
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Appearance: dendritis keratosis, painful hands
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Inheritance: AR
Rocky mountain spotted fever (RMSF)
Etiology:
Cause: Dermacentor variabilis, Dermacentor andersoni, Rhipicephalus
sanguineus
Description:
1. nonblanching rash initially appearing as red macules 1-5 mm in size and pruritic
2. within days the macules become papules, petechiae, and ecchymoses
3. in 50% of cases, rash becomes hemorrhagic
Location: begins on the ankles and wrists, then spreads to the palms and soles
Rosai Dorfman Disease
Etiology:
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Appearance:
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Histo: S100+
Rosacea
Etiology:
Ass. conditions: hyper/hypothyroid
Cause: inflammatory immune dysfunction that is triggered by stimuli (alcohol, caffeine, heat)
Description: erythematous papules and pustules on the face that can also develop rhinophyma
Rose Gardener’s Disease / Sporotrichosis
Etiology:
Cause: Sporothrix schenkii
Description: multiple inflammatory subcutaneous nodules in a linear fashion along the course of the lymphatic channels
Roseola / Exanthema Subitum / Sixth Disease
Etiology:
Cause: HHV-6 / HHV-7
Description: red lacy appearance (spares face), rose-colored macule (post high fever)
Rubella / German measles / 3 day measles
Etiology:
Cause: Rubella
Description: fine, erythematous, blanchable rash
Location: begin on the face and spreads down
Rubeola / Measles
Etiology:
Cause: measles virus (paramyxovirus)
Description: diffuse, blanchable, erythematous, maculopapular rash + blue-white Koplik spots on buccal mucosa
Location: rash begins at head and moving down