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U

Urticaria / Hives

Etiology: mast cell degranulation from allergic reaction (T1HS) or AutoAb to FcER1 (T2HS)

Appearance: wheals that disappear within 24 hours; surrounding erythema will blanch 

Sx: pruritus

Urticarial vasculitis

Etiology: rare inflammatory condition affecting small blood vessels in the skin

Appearance: wheals that will last longer than 24 hours

Prog: will go away in 1-3 years of onset

Tx: antihistamines, NSAIDs, CCS, immunosuppressant, omalizumab, dapsone

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