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Urticaria / Hives
Etiology: mast cell degranulation from allergic reaction (T1HS) or AutoAb to FcER1 (T2HS)
Appearance: wheals that disappear within 24 hours; surrounding erythema will blanch
Ass. conditions: angioedema
Sx: pruritus
Tx: avoid trigger, antihistamines (cetirizine, loratadine), omalizumab, cyclosporin
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Urticarial vasculitis
Etiology: rare inflammatory condition affecting small blood vessels in the skin
Ass. with: SLE, Sjogrens, leukemia, viral conditions, drug induced
Sx: painful or burning sensation
Appearance: wheals that will last longer than 24 hours
Prog: will go away in 1-3 years of onset
Tx: antihistamines, NSAIDs, CCS, immunosuppressant, omalizumab, dapsone
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