F

Familial Atypical Multiple Mole Melanoma syndrome (FAMMM syndrome)

Etiology:

Cause: AD mutation in CDKN2A gene causing

Description: >50 melanocytic nevi with a family history of melanoma

Female Pattern Hair Loss

Etiology:

Appearance: thinning, no shining, hair still present
Location: top of scalp, increased hair part width
Tx: topical minoxidil

Fibrous Hamartoma of Infancy

Etiology:

Histo: “ramen” waves (looks like nerve)
- Grey/blue ball cells = immature mesenchyme
- Mature fat that is honeycomb

Fixed Drug Eruption

Etiology:

Appearance:
- Early lesions: sharply demarcated erythematous macules
- Late lesions: round or oval plaques that may evolve to become bullae and then erosions (occur 30 min to 8 hours after ingesting drug)
Location: mouth, genitalia, face, acral
Prog: resolve days to weeks after drug is discontinued; PIH may persist

Folliculitis Decalvans

Etiology:

Appearance: red, swollen, and scaly patches, often with crusts and pustules; like CCCA, but smaller and with pustules
Sx: itching, pain, and a burning sensation
Tx: clindamycin, CCS (topical + oral or injected)

Focal Dermal Hypoplasia / Goltz Syndrome

Etiology:

Define: rare genetic disorder affecting tissues derived from the ectoderm and mesoderm, primarily impacting the skin, skeletal system, eyes, and face
Ass. conditions: coloboma, missing or webbed fingers
Inheritance: XLD
Appearance: thin or absent skin areas, hypopigmentation, hyperpigmentation, and fat herniation; follow Blaschko's lines; wart-like growths
Location: mouth, genitals, and anus

Frey's Syndrome

Etiology:

Cause = postoperative complication involving parasympathetic fibers regenerating on sympathetic fibers of sweat glands (auriculotemporal branch of V3 is cut during an excision of the parotid gland and reinnervates the skin sweat glands in front of the ear)

Description: redness + sweating in front of ears after eating, thinking, dreaming about food